Lyme disease is the most common vector-borne disease in the United States and, according to the Centers for Disease Control and Prevention, the areas where it is common are expanding.1,2
More than 30 million Americans are at high or moderate risk of contracting Lyme disease.2
Approximately 300,000-400,000 people are diagnosed with Lyme disease in the United States each year.2
Infected ticks are commonly found in the northeastern, mid-Atlantic, and northern central United States and cause Lyme disease by transmitting the bacterium Borrelia burgdorferi. The majority of humans are infected through the bite of immature ticks called nymphs, which are so small that they typically go undetected. In most cases, the tick must be attached for 36 to 48 hours or more before the Lyme disease bacterium can be transmitted.3
Untreated Lyme disease costs the US healthcare system up to $1.3 billion a year5
1. Recent surveillance data. US Centers for Disease Control and Prevention. Accessed August 11, 2023. https://www.cdc.gov/lyme/datasurveillance/recent-surveillance-data.html 2. Tarsus Pharmaceuticals, Inc. initiates phase 1 Callisto trial of TP-05, a novel, oral, non-vaccine therapeutic for the prevention of Lyme disease. Tarsus Pharmaceuticals, Inc. Press release. June 16, 2021. Accessed August 11, 2023. https://ir.tarsusrx.com/news-releases/news-release-details/tarsus-pharmaceuticals-inc-initiates-phase-1-callisto-trial-tp 3. Transmission. US Centers for Disease Control and Prevention. Accessed August 11, 2023. https://www.cdc.gov/lyme/transmission/index.html 4. Signs and symptoms of untreated Lyme disease. US Centers for Disease Control and Prevention. Accessed August 11, 2023. https://www.cdc.gov/lyme/signs_symptoms/index.html 5. Lyme disease costs up to $1.3 billion per year to treat, study finds. Johns Hopkins Bloomberg School of Public Health. Published February 5, 2015. Accessed August 11, 2023. https://www.jhsph.edu/news/news-releases/2015/lyme-disease-costs-more-than-one-billion-dollars-per-year-to-treat-study-finds.html
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